Journal of neurotrauma
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Journal of neurotrauma · Jul 2017
CommentGoldstein et al.'s secondary analysis of progesterone clinical trial for TBI can only reflect the same trial design flaws: A response to "Very Early Administration of Progesterone Does Not Improve Neuropsychological Outcomes in Subjects with Moderate to Severe Traumatic Brain Injury".
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Journal of neurotrauma · Jun 2017
Functional Outcome Prediction after Traumatic Spinal Cord Injury Based on Acute Clinical Factors.
Spinal cord injury (SCI) is a devastating condition that affects patients on both a personal and societal level. The objective of the study is to improve the prediction of long-term functional outcome following SCI based on the acute clinical findings. A total of 76 patients with acute traumatic SCI were prospectively enrolled in a cohort study in a single Level I trauma center. ⋯ In descending order, the best predictors for SCIM at 1 year were: LT, AIS grade, ISS, and AMS. One-year functional outcome (SCIM) can be estimated by a simple equation that takes into account four parameters of the initial physical examination. Estimating the patient long-term outcome early after traumatic SCI is important in order to define the management strategies that might diminish the costs and to give the patient and family a better view of the long-term expectations.