Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Analgesic effect of epidural neostigmine after abdominal hysterectomy.
To evaluate the effects of epidurally administered neostigmine on pain after abdominal hysterectomy. ⋯ Epidural neostigmine of 10 micro g/kg in bupivacaine provides a longer duration of analgesia than does bupivacaine alone or with 5 micro g/kg of neostigmine after abdominal hysterectomy.
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Randomized Controlled Trial Clinical Trial
Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: a prospective, randomized, double-blinded, placebo-controlled trial.
To evaluate the analgesic efficacy of the rofecoxib po before radical prostatectomy. ⋯ When rofecoxib is used po in maximum recommended doses before surgery, it does not provide significant analgesia that results in reduction in pain scores or analgesic requirements for patients after radical prostatectomy.
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Randomized Controlled Trial Clinical Trial
Hydroxyethyl starch (HES) does not directly affect renal function in patients with no prior renal impairment.
To examine the effects of hydroxyethyl starch (HES) on renal function. ⋯ Hydroxyethyl starch administration appears to be risk-free with regard to renal function in patients without preexisting renal dysfunction who undergo general anesthesia. The relevance of the decrease in aldosterone following HES therapy needs further investigation.