Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Evaluation of the safety and efficacy of epidural ketamine combined with morphine for postoperative analgesia after major upper abdominal surgery.
To evaluate the efficacy of the combination of epidural ketamine and morphine compared with epidural morphine alone for postoperative pain relief following major upper abdominal surgery. ⋯ The addition of epidural ketamine 1 mg/kg to morphine 50 microg/kg improved analgesia after major upper abdominal surgery without increasing side effects.
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Clinical Trial
Influence of pneumoperitoneum and patient positioning on respiratory system compliance.
To investigate the influence of pneumoperitoneum (PP) and posture on respiratory compliance and ventilation pressures. ⋯ Creation of PP at an IAP of 15 mmHg reduced respiratory system compliance, and increased peak inspiratory and mean airway pressures, which quickly returned to normal values after deflation. Head-down or head-up position did not further alter those parameters.