Journal of clinical anesthesia
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Observational Study
Thromboelastography does not reduce transfusion requirements in liver transplantation: A propensity score-matched study.
To compare total blood product requirements in liver transplantation (LT) assisted by thromboelastography (TEG) or conventional coagulation tests (CCTs). ⋯ In our experience, TEG-guided transfusion in LT does not reduce the intraoperative blood product consumption. Further studies are warranted to assess an advantage for TEG in either the entire LT population or the high-MELD subgroup of patients.
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We evaluated a department's long-term (6.5-year) success of achieving an overall and individual incidence of anesthesiologists working late of approximately 20% of days when not on call to work late, if necessary, and providing care in operating rooms. ⋯ An anesthesia department aiming for a 20% incidence of anesthesiologists having to work late when not on call can achieve this objective, long-term, within a few percent (e.g., 2%). Seasonal variation can contribute to variability among quarters in the overall departmental incidence. Individual anesthesiologists can have variability among themselves, though, and that is caused by large heterogeneity in their relative risks of working late when receiving relief versus when not handing off a case. For departments choosing to provide information to anesthesiologists to increase predictability, factors to consider should include season of the year and the individual anesthesiologist.
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To compare the effect of sedation protocols with and without dexmedetomidine on delirium risk and duration in adult patients in intensive care units (ICUs). ⋯ Low- or very low-quality evidence suggests that dexmedetomidine was associated with a clinically-small reduction of delirium risk, ICU/hospital stay and mechanical ventilation duration, but were not associated with improved mortality or shorter delirium duration in ICU patients. These findings were inconclusive because of publication bias, heterogeneity, and limited sample size. Significant adverse effects of dexmedetomidine include hypotension and bradycardia. PROSPERO registration number: CRD42018095358.