Current opinion in anaesthesiology
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Curr Opin Anaesthesiol · Apr 2014
ReviewMulticompartment management of patients with severe traumatic brain injury.
Intracranial pressure (ICP) control is a mainstay of traumatic brain injury (TBI) management. However, development of intracranial hypertension (ICH) may be affected by factors outside of the cranial vault in addition to the local effects of the TBI. This review will examine the pathophysiology of multiple compartment syndrome (MCS) and current treatment considerations for patients with TBI given the effects of MCS. ⋯ In MCS, intracranial, intrathoracic and intra-abdominal compartment pressures are interrelated. TBI patient care should include ICP control as well as minimization of intrathoracic and intra-abdominal pressure as clinically possible.
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Curr Opin Anaesthesiol · Apr 2014
Review Comparative StudyCost-efficiency of knowledge creation: randomized controlled trials vs. observational studies.
This article reviews traditional and current perspectives on randomized, controlled trials (RCTs) and observational studies relative to the economic implications for public healthcare stakeholders. ⋯ Considering the strengths and limitations of each study type, clinical researchers should explore the contextual worthiness of either design in promulgating knowledge. They should focus on quality of conduct and reporting that may allow for the liberation of limited public and private clinical research funding.
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Curr Opin Anaesthesiol · Apr 2014
ReviewThe changing anesthesia economic landscape: emergence of large multispecialty practices and Accountable Care Organizations.
In this review, we evaluate the current US employment models for healthcare in general and anesthesiologists in particular and the emergence of large, multispecialty physician groups and the forces behind this change to the current anesthesia practice model. We will also examine the present payment method for anesthesiologists and determine how Accountable Care Organizations will affect the future payment models. ⋯ This is the most critical time in the specialty of anesthesiology from an economic viewpoint, and significant threats and opportunities will arise for anesthesiologists in how they are reimbursed, and how they demonstrate the delivery of quality care to patients.
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In the perioperative period, acute heart failure can result from a variety of conditions, and treatment may vary considerably depending on its mechanism. This review aims to provide conceptual framework by selectively presenting recent knowledge and advances in acute heart failure therapies including drugs (inotropes, diuretics) and devices (mechanical assistance, biventricular pacing, ultrafiltration). ⋯ Poor data exist in the perioperative setting concerning acute heart failure therapies. Large trials are needed to support the use of levosimendan, mechanical assistance, utrafiltration and biventricular pacing in the perioperative setting. The prognostic role of natriuretic peptides was confirmed in the perioperative period.
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A large proportion of patients undergoing surgery have coexisting chronic kidney disease, placing them at greater risk of postoperative morbidity and mortality. The purpose of this review is to review the recent developments in how renal function is estimated, how this relates to surgical outcomes, and how this has been applied clinically. ⋯ Improved accuracy in defining kidney disease will aid clinicians in identifying higher risk patients, and aid earlier diagnosis of acute kidney injury. Further research is required, specifically on the implications of kidney disease in noncardiac surgical patients, and how defining renal function before and after surgery can aid in preventive strategies.