Gynecologic oncology
-
Gynecologic oncology · Sep 2014
Controlled Clinical TrialAnti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer.
Metformin has been associated with reduced cancer risk. The mechanisms underlying this cancer protective effect remain unknown. ⋯ This pilot trial presents biological evidence consistent with anti-proliferative effects of metformin in women with EC in the clinical setting.
-
Gynecologic oncology · Sep 2014
Diffusion of Enhanced Recovery principles in gynecologic oncology surgery: is active implementation still necessary?
Spontaneous diffusion of the evidence-based Enhanced Recovery After Surgery (ERAS) program from an early adopter department (colorectal surgery) to other closely related departments (gynecologic surgery) within the same hospital could be expected. Given this diffusion hypothesis, this quality improvement study examines the value of active implementation of ERAS in addition to spontaneous diffusion. ⋯ After several years of practicing ERAS in colorectal surgery, spontaneous spread of ERAS principles to gynecologic oncology surgery occurred partially. The results of this study underscore the need for a structured and supported pro-active process to implement the ERAS program in a complete and successful way.