BMJ : British medical journal
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Meta Analysis
Deviation from intention to treat analysis in randomised trials and treatment effect estimates: meta-epidemiological study.
To examine whether deviation from the standard intention to treat analysis has an influence on treatment effect estimates of randomised trials. ⋯ Trials that deviated from the intention to treat analysis showed larger intervention effects than trials that reported the standard approach. Where an intention to treat analysis is impossible to perform, authors should clearly report who is included in the analysis and attempt to perform multiple imputations.