Molecular neurobiology
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Molecular neurobiology · Aug 2002
ReviewContribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain.
Neuropathic pain is caused by nervous-system lesions. Early studies on the pathomechanisms of this abnormal pain state have focused on the directly injured fibers and neurons. ⋯ Electrophysiological changes and behavioral data also favor the contribution of the spared neurons. These attractive targets of study will give us new approaches for understanding the abnormal pain.