Medical principles and practice : international journal of the Kuwait University, Health Science Centre
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Randomized Controlled Trial
Can ephedrine pretreatment be effective in alleviating rocuronium injection pain?
The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effect of ephedrine pretreatment on the intensity of rocuronium injection pain when rocuronium was applied by timing principle and also to compare this effect with lidocaine and placebo. ⋯ Although not as effective as lidocaine 0.5 mg/kg, 70 μg/kg ephedrine pretreatment was able to alleviate rocuronium injection pain when rocuronium was applied by timing principle.