Applied nursing research : ANR
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To explore how growth trends may relate to maternal provision of breastmilk to preterm infants in the Neonatal Intensive Care Unit (NICU). ⋯ First oral feed being direct-to-breast and higher growth velocity are supportive of continued breastmilk provision throughout hospitalization. These results highlight a need for additional breastfeeding support for mother-infants dyads who provided a bottle as the first oral feed or with poorer growth progression.
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When codeine and tramadol are used for pain management, it is imperative that nurses are able to assess for potential drug-gene and drug-drug-gene interactions that could adversely impact drug metabolism and ultimately pain relief. Both drugs are metabolized through the CYP2D6 metabolic pathway which can be affected by medications as well the patient's own pharmacogenotype. The purpose of this brief report is to identify drug-gene and drug-drug-gene interactions in 30 adult patients prescribed codeine or tramadol for pain. ⋯ Our findings from this exploratory study underscores the importance of assessing and accounting for drug-gene and drug-drug-gene interactions in patients prescribed codeine or tramadol.