Journal of anesthesia
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Journal of anesthesia · Sep 1994
Assessment of postoperative pain: Contributing factors to the differences between patients and doctors.
This study was undertaken to compare the assessment of pain intensity by 50 patients and by their doctors according to a visual analog scale 5 h and 20 h after major abdominal surgery, and to examine the relationships between the differences in rating of patients and doctors and the factors inherent in the patients which include preoperative expectation of pain, level of anxiety, and the surgical history of the patient. The ratings given by the patients were significantly higher than those given by the doctors at both time periods. ⋯ The results of analysis using Hayashi's quantification theory Type II indicated a moderate association between the rating difference and the patient's age, surgical history, preoperative state of anxiety, and expectation of pain. It is concluded that postoperative pain management, whether in clinical practice or in research, necessitates more consideration of the several above-mentioned individual factors and a preoperative interview in which the patient's level of anxiety and the amount of information the patient has concerning the surgery and post-operative pain is clearly assessed.
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Journal of anesthesia · Sep 1994
Crossover effects of acidosis on the recovery of neuronal function following glucose-oxygen deprivation in rat hippocampal slices.
The present study was designed to determine whether acidosis modifies the effect of simulated ischemia on neuronal function. Hippocampal evoked potentials were recorded in vitro from the CA1 region after stimulation of the Schaffer collaterals and the change in the evoked potentials was analyzed in response to glucose-oxygen deprivation under variable acid-base conditions ranging from pH 7.4 to pH 4.5. ⋯ The recovery of PS amplitude during recovery from glucose-oxygen deprivation was not significantly inhibited by moderate acidosis of pH 6 and 5.5 but was significantly inhibited when the pH was 5 or lower. The results suggest that severe acidosis may depress PS amplitude and prevent their recovery after reversal of glucose-oxygen deprivation, and that moderate acidosis may have no significant effect on PS amplitudes on their recovery.
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Journal of anesthesia · Sep 1994
Effects of halothane and enflurane on the peripheral vasoconstriction and shivering induced by internal body cooling in rabbits.
General anesthetic agents have central and peripheral effects on body temperature regulation, and its alterations are related to the depth of anesthesia. To evaluate the effect of halothane and enflurane on thermoregulation, we investigated the threshold of body core temperatures to induce peripheral vasoconstriction and shivering in spontaneously breathing rabbits. Rabbits were anesthetized with halothane or enflurane at 0.0 (control), 0.2, and 0.4 MAC (minimum alveolar concentration). ⋯ The incidence of peripheral vasoconstriction was not significantly affected by halothane or enflurane. However, the incidence of shivering decreased in a dose-dependent fashion with both anesthetic agents. At 0.2 MAC, the incidence of shivering in the enflurane group was significantly higher than that in the halothane group, suggesting that suppression of shivering by halothane is stronger than enflurane.