Journal of anesthesia
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Journal of anesthesia · Dec 1997
Target controlled priming for rapid onset of intubation dose: A new approach.
To determine the pattern of onset of the intubating dose when given at a monitored target priming block in either phase of the priming drug effect. ⋯ In conclusion, target controlled priming (DBSr) for administration of the intubating dose appears to be a useful double-vision sign to predict the onset of the effect of the intubating dose precisely.
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Journal of anesthesia · Dec 1997
Effect of fentanyl on heart rate variability during mechanical ventilation.
This study was performed to investigate the effect of fentanyl alone on heart rate variability (HRV) during mechanical ventilation using power spectral analysis. Arterial baroreceptor reflex was also tested with pharmacological manipulation to assess the contribution of vagal baroreceptor reflex modulation of HRV during fentanyl anesthesia. ⋯ Our data indicate that fentanyl modulates the respiratory frequency fluctuation of HRV. This is partly caused by the effects of fentanyl on arterial baroreflex sensitivity.
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Journal of anesthesia · Dec 1997
Normothermic cardiopulmonary bypass and cardioplegia reduce inotropic requirements and creatine kinase-MB after coronary artery bypass graft surgery.
To determine whether normothermic cardiopulmonary bypass (CPB) and cardioplegia preserve myocardial function, reduce inotropic requirements, and reduce markers of myocardial ischemia following coronary artery bypass graft surgery (CABG). ⋯ Normothermic CPB and cardioplegia reduce inotropic requirements and CK-MB following CABG.
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Journal of anesthesia · Dec 1997
Effects of hemoglobin concentration and temperature on the in vitro release of cyanide from sodium nitroprusside.
This in vitro study was performed to determine whether changes in hemoglobin (Hb) concentration and temperature influenced the amount of cyanide (CN-) released from sodium nitroprusside (SNP). ⋯ Though the Hb concentration and temperature changed the amount of CN- released from SNP in RBC, the change observed was not clinically significant.
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Journal of anesthesia · Dec 1997
Effect of inhaled nitroglycerine and sodium nitroprusside aerosol on hemodynamics and oxygenation in dogs with pulmonary hypertension.
To test the hypothesis that inhalation of aerosol of glyceryl trinitrate or sodium nitroprusside might produce selective pulmonary vasodilation, causing an improvement of oxygenation with minimal systemic hypotension as inhaled nitric oxide gas, we investigated the effect of inhaled nitroglycerine and sodium nitroprusside aerosol on hemodynamics and oxygenation in dogs with pulmonary hypertension. ⋯ These findings suggest that inhaled nitroglycerine and sodium nitroprusside aerosol is not effective in improving hemodynamic derangement or oxygenation in pulmonary hypertension. However, the effect of the substances in higher dose ranges remains to be defined.