Journal of anesthesia
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Cardiac surgery-associated acute kidney injury (AKI) is a major health problem that is extremely common and has a significant effect on cardiac surgical outcomes. AKI occurs in nearly 30 % of patients undergoing cardiac surgery, with about 1-2 % of these ultimately requiring dialysis. The development of AKI predicts a significant increase in morbidity and mortality independent of other risk factors. ⋯ Risk factors for AKI have been identified in several models, and these facilitate physicians to prognosticate and develop a strategy for tackling patients predisposed to developing renal dysfunction. Effective therapy of the condition is still suboptimal, and hence the accent has always been on risk factor modification. Thus, strategies for reducing preoperative anemia, perioperative blood transfusions and surgical re-explorations may be effective in attenuating the incidence and severity of this complication.
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Journal of anesthesia · Jun 2013
Retraction Of PublicationRetraction note: Further notice of formal retraction of articles by Dr. Yoshitaka Fujii.
Retraction to: J Anesth (1997) 11:126–129DOI 10.1007/BF02480074,J Anesth (1996) 10:22–25DOI 10.1007/BF02482063,J Anesth (1996) 10:176–180DOI 10.1007/BF02471386,J Anesth (1995) 9:58–60DOI 10.1007/BF02482037,J Anesth (1995) 9:343–347DOI 10.1007/BF02479949,J Anesth (1994) 8:301–304DOI 10.1007/BF02514655. To readers of the Journal of Anesthesia: In addition to the articles listed in a retraction note in JAnesth (2013) 27:322, the following articles published by Dr. Yoshitaka Fujii in the Journal of Anesthesia also are hereby retracted as a result of: (1) overwhelming evidence of fabrication related to the fact that the distributions of many variables reported by Dr. ⋯ J Anesth. 1996;10:22–5.*Fujii Y, Toyooka H. Nicardipine inhibits amrinone-enhanced contractility in fatigued diaphragm. J Anesth.1997;11:126–9.
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Journal of anesthesia · Jun 2013
Randomized Controlled TrialComparison of the use of the Valsalva maneuver and the eutectic mixture of local anesthetics (EMLA®) to relieve venipuncture pain: a randomized controlled trial.
Intravenous cannulation is a painful and stressful procedure. The objective of this study was to compare the analgesic efficacy of the eutectic mixture of local anesthetics (EMLA(®)) with that of the Valsalva maneuver in adult patients during i.v. cannulation. ⋯ The Valsalva maneuver yields similar results to the EMLA(®) in terms of pain reduction during venipuncture.
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Journal of anesthesia · Jun 2013
Randomized Controlled Trial Multicenter StudyA prospective randomized multicenter comparative study of BLM-240 (desflurane) versus sevoflurane in Japanese patients.
The present study was conducted to evaluate the efficacy and safety of BLM-240 (desflurane) in comparison to sevoflurane in Japanese patients. A total of 216 patients were enrolled in this randomized comparative study at 15 medical institutions. The patients received either BLM-240 with 50-70 % N2O in O2 (n = 111), BLM-240 with 30 % O2 in air (n = 55), or sevoflurane with 50-70 % N2O in O2 (n = 50). ⋯ Time from discontinuation of anesthetic delivery to extubation was 9.7 ± 0.6 min in the BLM-240/N2O group and 14.3 ± 0.9 min in the sevoflurane/N2O group, meeting the pre-defined non-inferiority criteria of BLM-240 to sevoflurane. There was no statistically significant difference in the incidence of total ADR between the BLM-240 group (62.0 %) and sevoflurane group (48.0 %). The results indicate that BLM-240 is an effective and safe inhalation anesthetic in Japanese patients.