Journal of anesthesia
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Journal of anesthesia · Feb 2025
Preoperative hypoxic biomarkers and postoperative delirium in patients with obstructive sleep apnea.
Postoperative delirium (POD) in patients with obstructive sleep apnea (OSA) is associated with increased mortality and healthcare costs. In this study, we investigated the association of OSA risk, serum biomarkers for central nervous ischemia (S100B and NSE), and POD. ⋯ We found a trend of decreasing POD incidence with increasing OSA risk, which was not robust in a complete case analysis. Our results possibly support the phenomenon of hypoxic preconditioning.