Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
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Comparative Study
An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma.
Nasal polyposis occurs frequently in patients with intrinsic asthma, especially in those who are aspirin sensitive. It can be difficult to treat effectively, even with surgery and regular topical intranasal corticosteroids many patients are still symptomatic. ⋯ The findings are consistent with a subgroup of nasal polyps/asthma patients in whom leukotriene receptor antagonists are effective. This is not related to aspirin sensitivity. Further placebo-controlled studies need to be undertaken.