Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
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Comparative Study Controlled Clinical Trial
Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
To confirm allergy to beta-lactam (BL), a basophil activation test in flow cytometry based on CD63 up-regulation was described. CD203c is a more recent basophil activation marker and up to day there is no consensus about which marker is the more sensitive one. CD203c has not yet been evaluated in the diagnosis of BL allergy. ⋯ CD203c seems to be a more sensitive activation marker of basophils than CD63 for the diagnosis of amoxicillin allergy.
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To date, there is no food allergy-specific questionnaire that allows parents to report children's health-related QoL (HRQL) from the child's perspective. ⋯ The FAQLQ-PF is psychometrically robust, with excellent reliability and validity.