Pneumologie
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Multicenter Study Clinical Trial Controlled Clinical Trial
[Bupropion SR for weaning from smoking in relapsed smokers: results of an open multicentre trial in Germany].
After initially successful smoking cessation the majority of patients relapse which stresses the addiction character of nicotine dependence. The patient and the physician, in therapeutic nihilism will not make another attempt for smoking cessation. In two randomised, double-blind, placebo-controlled trials in the US and Canada relapsed smokers, who had initially successfully quit smoking under Bupropion SR (Zyban), were again treated with Bupropion SR for smoking cessation. The encouraging results prompted us to perform a study in Germany under the conditions and temporal restraints of a routine medical practice. ⋯ Bupropion SR was effective and well tolerated when given as an aid in smoking cessation in relapsed smokers.