Journal of interventional cardiology
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It has been suggested that a left atrial (LA) dysfunction induced by large shunt and large atrial septal aneurysm (ASA) may act as a concurrent mechanism of arterial embolism in patients with patent foramen ovale (PFO) and prior stroke. We aimed to evaluate the potential contribution of this mechanism as trigger of migraine in patients with PFO. ⋯ This study suggests that LA dysfunction probably does not contribute to migraine itself but may play a role in the genesis of aura symptoms.