Journal of psychopharmacology
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J. Psychopharmacol. (Oxford) · Jun 2020
Observational StudyMicrodosing psychedelics: Demographics, practices, and psychiatric comorbidities.
Microdosing psychedelics - the practice of consuming small, sub-hallucinogenic doses of substances such as LSD or psilocybin - is gaining attention in popular media but remains poorly characterized. Contemporary studies of psychedelic microdosing have yet to report the basic psychiatric descriptors of psychedelic microdosers. ⋯ Well-designed randomized controlled trials are needed to evaluate the safety and tolerability of this practice in clinical populations and to test claims about potential benefits.
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J. Psychopharmacol. (Oxford) · Jun 2020
Evaluating the co-use of opioids and cannabis for pain among current users using hypothetical purchase tasks.
Cannabinoids may potentiate opioid analgesia and therefore could be used to reduce reliance on opioids for analgesia. ⋯ These data provide behavioral economic evidence that cannabis access may modestly reduce demand for opioids in persons who have pain. Additional clinical studies that evaluate the analgesic effects of cannabis and cannabis-opioid effects on pain are warranted.