Respiratory medicine
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Respiratory medicine · Jan 2006
Randomized Controlled Trial Comparative StudyTwo different training programmes for patients with COPD: a randomised study with 1-year follow-up.
To compare the effects on exercise capacity and health related quality of life (HRQoL) of two exercise programmes; one programme including endurance training and one including only resistance training and callisthenics. A second purpose was to find out whether the severity of chronic obstructive pulmonary disease (COPD) affected the training response and whether the interventions had a long-term effect. ⋯ Exercise capacity in patients with severe and moderate COPD improved by intensive endurance training, two sessions a week for 8 weeks. The improvement was however small and HRQoL did not improve. Severity of illness did not affect response to training. The results indicated that the effects of a short endurance training intervention slowed down decline in baseline functional exercise capacity for 1 year.
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Respiratory medicine · Jan 2006
Predictors of hospital outcome and intubation in COPD patients admitted to the respiratory ICU for acute hypercapnic respiratory failure.
Mortality rate, the possible factors affecting mortality and intubation in patients with acute exacerbation of chronic obstructive pulmonary diseases (COPD) and hypercapnic respiratory failure (RF) are yet unclear. ⋯ The most important predictors related to hospital mortality were the need for invasive ventilation and complications to MV. Adequate metabolic compensation for respiratory acidosis at admittance is associated with better survival. A high APACHE II score and loss of consciousness (low GCS) were independent predictors of a need to intubate patients.
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Respiratory medicine · Jan 2006
Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality: findings from the Atherosclerosis Risk in Communities (ARIC) study.
To determine whether a modified Global Initiative on Obstructive Lung Diseases (GOLD) classification of chronic obstructive pulmonary disease (COPD) predicts mortality in a cohort of subjects followed for up to 11 years. ⋯ The modified GOLD classification system of COPD predicts mortality in this cohort of middle-aged Americans followed for up to 11 years.
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Respiratory medicine · Jan 2006
Quantitative assessment of emphysema distribution in smokers and patients with alpha1-antitrypsin deficiency.
Identification of upper lobe emphysema is mandatory before lung volume reduction surgery (LVRS). Here we introduce a CT-based objective model for describing the distribution of different types of emphysema. ⋯ The majority of patients with smoking-related emphysema have a homogeneous distribution and lower lobe predominance although not as noticeable as in alpha1-antitrypsin deficiency. An objective and quantitative method for determining the distribution of emphysema should be applied when selecting candidates for LVRS.