Respiratory medicine
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Respiratory medicine · Oct 2010
Randomized Controlled Trial Multicenter StudyBudesonide added to formoterol contributes to improved exercise tolerance in patients with COPD.
Breathlessness and exercise intolerance frequently impact the daily life of patients with COPD. ⋯ Budesonide/formoterol resulted in a significant improvement in endurance time 1 h after the last morning dose in a 1-week treatment period versus formoterol and placebo. This study demonstrates, for the first time, the benefit of inhaled corticosteroids in addition to long-acting beta(2)-agonists on exercise tolerance in COPD patients. www.clinicaltrials.gov registration number: NCT00489853.
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Respiratory medicine · Oct 2010
Randomized Controlled Trial Multicenter StudyA one-year trial of tiotropium Respimat plus usual therapy in COPD patients.
In this randomised double-blind study, patients >or=40 years old with COPD, a smoking history of >or=10 pack-years, a pre-bronchodilator FEV(1) of
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Respiratory medicine · Oct 2010
Clinical analysis of patients with pulmonary lymphangioleiomyomatosis (PLAM) in mainland China.
There have been no clinical reports on pulmonary lymphangioleiomyomatosis (PLAM) based on large studies or epidemiological surveys in mainland China. The purpose of this study was to provide a retrospective analysis of PLAM patients in mainland China by reviewing the clinical data of PLAM cases reported. ⋯ Doctors in mainland China are becoming increasingly vigilant to PLAM, although misdiagnosis or missed diagnosis still exists. Provider attention to the correlation between PLAM and tuberous sclerosis complex, as well as to the possible involvement of multiple organs, is insufficient.
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Respiratory medicine · Oct 2010
A proposal of a new model for long-term weaning: respiratory intensive care unit and weaning center.
Respiratory intermediate care units (RICU) are hospital locations to treat acute and acute on chronic respiratory failure. Dedicated weaning centers (WC) are facilities for long-term weaning. ⋯ The sequential activity of a RICU and a WC resulted in additive weaning success rate of difficult-to wean patients. The cost-benefit ratio of the program warrants prospective investigations.