Urology
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To compare 3 kinds of topical hemostatic agents in terms of adhesive strength, control of hemorrhage, and postoperative intra-abdominal adhesions in an experimental partial nephrectomy (PN) model. ⋯ In our rat model, chitosan and the hemostatic plant extract were as effective as conventional suturing in achieving hemostasis even without hilar control. Warm ischemia was eliminated and PN time was significantly decreased. The use of oxidized cellulose was not associated with higher scores of adhesion, suppuration, or hematoma.
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To determine the incidence and morbidity of surgical site infections (SSI) during prostatectomy, and determine the association with surgical approach. The development of a SSI after radical prostatectomy is associated with increased cost and significant morbidity. However, existing comparisons between open and robotic surgery have been made comparing a contemporary robotic experience with historical cohorts undergoing open surgery. ⋯ Patients undergoing RARP are less likely to develop SSIs than patients undergoing RRP. Furthermore, the infections that develop after minimally invasive surgery are less severe. Continued investigation into the mechanisms of SSIs are needed to further decrease patient morbidity.
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To investigate the association of CYP17 polymorphism with 17β-estradiol (E2) and testosterone (T) concentration in hypospadias. ⋯ Our study suggests that, although polymorphism in CYP17 gene may not be associated with 17β-E2 and T concentrations in hypospadias cases, low levels of T and higher E2/T ratio might possibly act as risk factors for hypospadias.