Journal of neurosurgical anesthesiology
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J Neurosurg Anesthesiol · Oct 2011
Randomized Controlled TrialEffects of prone and jackknife positioning on lumbar disc herniation surgery.
Intra-abdominal hypertension due to surgical position increases bleeding at the surgical site. In this study, we evaluated the impact of prone and jackknife position on intra-abdominal pressure (IAP), lung mechanics, blood loss at the surgical site, and duration of the surgical procedure on lumbar disc operations. ⋯ The jackknife position causes less IAP elevation and less surgical site bleeding compared with the prone position. The jackknife position is the preferred choice for single-level lumbar disc surgery in healthy, nonobese patients.
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J Neurosurg Anesthesiol · Oct 2011
Randomized Controlled TrialEfficacy of prophylactic low dose of tranexamic acid in spinal fixation surgery: a randomized clinical trial.
Spinal fixation surgery is potentially associated with significant bleeding, often requiring multiple blood transfusions. Concern for the risks of transfusion-acquired infection and immune modulation effects of allogeneic blood has led to the investigation of various hemostatic agents such as tranexamic acid (TXA). The investigators hypothesized that a prophylactic low dose of TXA would reduce blood loss and transfusion requirements during spinal fixation surgery. ⋯ The administration of a prophylactic low dose of TXA did not have a significant effect in the management of intraoperative blood loss and transfusion requirements in patients undergoing spinal fixation surgery.