The Journal of neuropsychiatry and clinical neurosciences
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J Neuropsychiatry Clin Neurosci · Jan 1992
Case ReportsOrganic mood disorder associated with the HAIR-AN syndrome.
The HAIR-AN syndrome is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. The authors report the first case of an organic mood disorder associated with this condition that improved markedly in response to ovarian suppression with oral contraceptives. The proposed pathophysiology of this syndrome is also discussed.
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J Neuropsychiatry Clin Neurosci · Jan 1992
Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia.
Cognitive impairment varies markedly among schizophrenic individuals, although the reason for this is unknown. A monozygotic twin pair concordant for schizophrenia was evaluated using electrophysiological and neurobehavioral measures. Each twin showed a distinctive pattern of deficits; furthermore, clinical course and electrophysiological activity were not consonant with social and neurobehavioral functioning. Results suggest complex interrelationships between neurocognitive functioning and clinical presentation in schizophrenia.