Critical care nursing clinics of North America
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Treatment options for patients with malignant primary and metastatic lesions to the brain are limited and offer little therapeutic benefit. Despite the use of conventional therapy survival of patients is measured in weeks and months. The use of gene therapy with ganciclovir administration and immunotherapy using targeted protein toxins are two experimental approaches to improving this poor prognosis through regional therapy.
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This article describes the unit-based advanced practice nurse (APN). A review of the literature provides historic development of the concept. ⋯ A case example demonstrates the success of the role in terms of patient outcomes. Future trends for the APN are also explored.