American journal of reproductive immunology : AJRI
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Am. J. Reprod. Immunol. · Nov 1997
Induction of autoimmune prostatitis using liposomes is associated to peritoneal cells activation.
Study and characterization of rat peritoneal cells (PC) involved in the induction of autoimmune prostatitis after the intraperitoneal administration of native extract of accessory glands (RAG) associated with liposomes (RAGL). ⋯ Our results suggest that the effective uptake of liposomes and the initial activation of PC together with a prolonged stimulatory effect help to disrupt the tolerance state. The present experimental model is an interesting approach to further characterize events associated with antigenic presentation when an autoimmune response is triggered.