Topics in magnetic resonance imaging : TMRI
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Top Magn Reson Imaging · Aug 2006
ReviewMagnetic resonance and diffusion tensor imaging in pediatric white matter diseases.
The central nervous system undergoes profound and predictable developmental changes during the first few years of life that provide the structural and functional elements necessary for normal neurological development. The establishment and maturation of white matter pathways is a critical component of the developing nervous system. ⋯ Furthermore, it has helped characterize the relation between white matter integrity and cognitive abilities. In the future, DTI is expected to play an increasingly large role in defining developmental abnormalities at an early age and in assessing therapies for pediatric disorders such as leukodystrophies.