Allergologia et immunopathologia
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Allergol Immunopathol (Madr) · Jul 2010
Comparative StudySpecific pattern of flea antigen recognition by IgG subclass and IgE during the progression of papular urticaria caused by flea bite.
Papular urticaria caused by flea bite presents clinical symptoms of a hypersensitivity reaction accompanied by skin lesions. However, the pattern of recognition by different antibody isotypes during the progression of the disease is unknown. This study evaluated variations in immunoglobulin E and immunoglobulin G subclass antibody responses to flea antigens during the progression of papular urticaria caused by flea bite ⋯ The predominant specific antibody isotypes vary according to the time elapsed since the onset of symptoms in papular urticaria caused by flea bite.