Allergologia et immunopathologia
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Allergol Immunopathol (Madr) · Jan 2014
Case ReportsImmediate hypersensitivity to chlorhexidine is increasingly recognised in the United Kingdom.
Chlorhexidine is widely used as an antiseptic agent. It is a potentially allergenic substance that can cause severe hypersensitivity reactions. ⋯ Immediate hypersensitivity to chlorhexidine appears to be common but underreported in the UK. We recommend that centres investigating patients with reactions during anaesthesia and surgery should routinely include testing for chlorhexidine allergy.
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Allergol Immunopathol (Madr) · Jan 2014
Utility of opium seed extract tests in preventing hypersensitivity reactions during surgery.
Anaphylaxis during anaesthesia is fatal in 3-9% of patients and analgesics, including opioids, and is the second most common medicament-related cause, although the prevalence is underestimated. We recently found that patients may generate IgE antibodies to opium seeds. ⋯ Sensitivity to opioids and intraoperative anaphylaxis can be diagnosed by routine tests. IgE and skin tests for the oil body fraction of P. somniferum had the highest sensitivity for sensitisation to opioids.
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Allergol Immunopathol (Madr) · Jan 2014
Diagnostic accuracy of atopy patch tests for food allergy in children with atopic dermatitis aged less than two years.
Atopy patch tests (APT) have been introduced as a valuable tool for the diagnosis of food allergy. However, interpretation of the readout of APT requires further clarification. ⋯ The APT is a suitable method for the diagnosis of AD in Chinese children aged less than two years with food allergies. Erythema and infiltration are not sufficient indicators of APT positivity. The PPV increases with indurations and the number of papules.