European journal of gastroenterology & hepatology
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Eur J Gastroenterol Hepatol · Feb 1999
Ileogastrostomy or jejunoileal bypass with drainage of the bypassed bowel into the stomach.
Ileogastrostomy was first performed for morbid obesity in 1982. In this review, the rationale and technique for the operation are described, and the results and complications discussed. ⋯ The surgery is simple to perform and achieves excellent weight loss and reversal of co-morbid conditions such as non-insulin-dependent diabetes mellitus, but requires long-term follow-up. The principal long-term problem is calcium oxalate renal stones, with occasional patients having troublesome diarrhoea.
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Eur J Gastroenterol Hepatol · Feb 1999
Basal and stimulated gastrin and pepsinogen levels after eradication of Helicobacter pylori: a 1-year follow-up study.
A decrease in gastrin and pepsinogen (PG) levels 1 month after Helicobacter pylori eradication has been described repeatedly, but the long-term progression of such a decrease has been scarcely studied. We therefore studied the effect of H. pylori eradication on basal and stimulated gastrin and PG levels for 1 year. Initially, the usefulness of measuring these parameters for the noninvasive diagnosis of H. pylori eradication was validated. Furthermore, an assessment was made of the association between H. pylori reinfection and a re-increase in gastrin and PG values. Finally, an evaluation was made of the variables influencing gastrin and PG concentration, with particular attention to H. pylori infection and histological lesions of gastric mucosa. ⋯ (1) Measurement of gastrin and PG levels (especially basal PGII values) is a useful non-invasive method to confirm H. pylori eradication after therapy. (2) H. pylori eradication is associated with a significant decrease in basal and stimulated gastrin levels and in basal PGII levels that is detected immediately (1 month) after finishing treatment, and remains unchanged for 1 year. However, the decrease in basal and stimulated PGI levels occurs progressively for 6 months, although such levels remain also unchanged afterwards. (3) Measurement of gastrin and PGI concentrations has a limited usefulness in the diagnosis of H. pylori reinfections after successful eradication, although PGII determination could be more useful in this situation.