European journal of gastroenterology & hepatology
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Eur J Gastroenterol Hepatol · Apr 2018
Comparative StudyNoninvasive fibrosis markers and chronic kidney disease among adults with nonalcoholic fatty liver in USA.
Studies have shown that nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of chronic kidney disease (CKD). However, it is unknown whether severe liver fibrosis is associated with a higher prevalence of CKD among NAFLD. We examined the diagnostic performance of noninvasive fibrosis markers in identifying prevalent CKD among NAFLD. ⋯ Advanced liver fibrosis, defined by NFS and FIB-4 scores, is associated independently with CKD among individuals with NAFLD. FIB-4 is the best predictor of an increased risk of prevalent CKD.