European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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Eur Arch Otorhinolaryngol · Jan 1995
Case ReportsAsymptomatic carotid artery occlusion from a gunshot. The role of angiography in penetrating neck trauma.
Recognition of a carotid artery injury after a gunshot neck wound can be difficult to make in the absence of physical signs. Currently, the usefulness of preoperative angiography in detecting penetrating neck trauma is controversial. We present a case of an angiography proven asymptomatic carotid artery occlusion after a gunshot. Indications for angiography after neck trauma are discussed.
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Carcinoma of the tonsil is the second most common malignancy of the head and neck. Various studies have attempted to define the presentation, diagnosis, treatment, and prognosis of these tumors. This report reviews the currently available information on tonsillar carcinoma and discusses treatment options.
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Eur Arch Otorhinolaryngol · Jan 1995
Comparative StudyCytokines in neutrophil-dominated airway inflammation in patients with cystic fibrosis.
Bronchopulmonary disease in patients with cystic fibrosis (CF) is a paradigm of neutrophil-dominated airway inflammation. We hypothesized that proinflammatory cytokines contribute to a localized neutrophil-dominated inflammatory state as present in CF airways. In a cross-sectional study, we analyzed 63 sputum samples from 33 CF patients for concentrations of the cytokines interleukin-1 alpha (IL-1 alpha), IL-1 beta, IL-8, tumor necrosis factor-alpha (TNF-alpha), and granulocyte-colony stimulating factor (G-CSF) by means of enzyme-linked immunosorbent assay. ⋯ In CF patients with airways chronically colonized with Pseudomonas aeruginosa, IL-8 concentrations in sputum were significantly enhanced. In glucocorticoid-treated patients, IL-1 alpha and G-CSF sputum concentrations were significantly lower when compared to levels in the other patients. These results show that there are high concentrations of proinflammatory cytokines in CF airways which may contribute to the localized neutrophil-dominated inflammatory state found clinically.
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Eur Arch Otorhinolaryngol · Jan 1995
Case ReportsA petrous bone destructive acoustic neurinoma: a tumor of far-lateral origin?
We report a case of an acoustic neurinoma that recurred more than 11 years after "total" tumor removal through the posterior cranial fossa. Recurrent tumor had obliterated the petrous bone, filled the middle ear, and was visible grossly at the external auditory meatus. The unique behavior of this tumor implied that the site of origin was within the labyrinth, beyond the fundus of the internal auditory canal and far lateral to the usual site of acoustic neurinoma origin. We offer an hypothesis as to why these tumors occasionally recur, even after clinical "total" removal.