The British journal of dermatology
-
Randomized Controlled Trial Multicenter Study Clinical Trial
Histological effects of tazarotene 0.1% cream vs. vehicle on photodamaged skin: a 6-month, multicentre, double-blind, randomized, vehicle-controlled study in patients with photodamaged facial skin.
Topical tazarotene has been shown to offer efficacy in ameliorating multiple effects of photodamage. ⋯ Treatment of photodamaged skin with tazarotene is associated with an amelioration of keratinocytic and melanocytic atypia, an improvement in epidermal polarity, and an increase in epidermal thickness.