The British journal of dermatology

The most recent articles from: Br. J. Dermatol. July 2012

Br. J. Dermatol. · Jul 2012

Randomized Controlled Trial Multicenter Study

Successful treatment of moderate to severe plaque psoriasis with the PEGylated Fab' certolizumab pegol: results of a phase II randomized, placebo-controlled trial with a re-treatment extension.

Certolizumab pegol (CZP) is a PEGylated antitumour necrosis factor agent. ⋯ Treatment with CZP significantly improved psoriasis at week 12. Similar efficacy was observed at week 12 in patients receiving re-treatment for loss of response after drug withdrawal.

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Br. J. Dermatol. · Jul 2012

Association between HLA-B*58:01 allele and severe cutaneous adverse reactions with allopurinol in Han Chinese in Hong Kong.

Allopurinol has been reported as a common cause of severe cutaneous adverse reactions (SCARs). Recent studies in various populations suggest that HLA-B*58:01 is a strong genetic marker for allopurinol-induced SCAR, especially in populations with a high frequency of HLA-B*58:01. ⋯ This study confirmed the strong association between the HLA-B*58:01 and allopurinol-induced SCAR in Hong Kong Han Chinese patients. A screening test for the HLA-B*58:01 allele should effectively reduce the risk for allopurinol-induced SCAR in Chinese populations.

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Br. J. Dermatol. · Jul 2012

Letter

Medical professional involvement in smartphone 'apps' in dermatology.

no abstract available

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