European journal of internal medicine
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Eur. J. Intern. Med. · Mar 2020
Cardiovascular target organ damage in premenopausal systemic lupus erythematosus patients and in controls: Are there any differences?
to analyze the presence of cardiac and vascular preclinical damage in premenopausal women with systemic lupus erythematosus (SLE) and controls, matched for demographic characteristics and for other cardiovascular risk factors. ⋯ in young patients with SLE and low activity index of the disease, we did not observe significant vascular alterations as compared to controls with similar CV risk. The early LV systolic impairment observed in SLE patients needs confirmation.
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Eur. J. Intern. Med. · Mar 2020
Review Meta AnalysisSpeckle tracking echocardiography in patients with systemic lupus erythematosus: A meta-analysis.
Systemic lupus erythematosus (SLE), is characterized by a systemic involvement including myocardial dysfunction. Being standard echocardiography not able at fully detecting subclinical alterations, speckle tracking echocardiography (STE) has recently emerged as a quantitative ultrasound technique to accurately estimate myocardial function. ⋯ SLE patients have lower STE parameters than controls, thus suggesting the presence of an impaired myocardial function involving both left and right ventricle.