Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jun 1980
Anesthesia for cesarean section.--VI Late effects on the infant of enflurane anesthesia for cesarean section.
Enflurane anesthesia for cesarean section has given favourable results with regard to anesthetic effect and lack of depression of the neonate. Enflurane is metabolized to fluoride. High serum levels of inorganic fluoride are nephrotoxic. ⋯ To exclude unwanted effects on the children, a follow-up study was undertaken 6-12 months after delivery. General development and renal function were studied. No abnormalities were found, indicating that enflurane anesthesia for cesarean section has no persistent unfavourable effects on the children.
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Acta Anaesthesiol Scand · Jun 1980
Comparative StudyTemperature variations in disposable heat and moisture exchangers.
Temperature variations in different parts of three heat and moisture exchangers (HME) were measured during spontaneous breathing. Temperatures below ambient occurred in the distal part of two of them. The lowest temperatures recorded were more than 6 degrees C below room temperature. This effect can explain why gas expired through a good HME is not saturated with water at ambient temperature.
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Acta Anaesthesiol Scand · Jun 1980
Anesthesia for cesarean section--VII. Early effects on neonatal renal function of enflurane anesthesia for cesarean section.
Fourteen women undergoing elective cesarean section were anesthetized with enflurane for induction and maintenance of anesthesia. Blood enflurane and serum inorganic fluoride levels were studied in the mothers at delivery and in the neonates at delivery and in the early neonatal period. Also neonatal urinary excretion of inorganic fluoride was determined. ⋯ The level of inorganic fluoride in urine was higher than the corresponding serum level, indicating an inorganic fluoride concentrating effect of the neonatal kidney. The difference between urinary excretion and serum content of inorganic fluoride showed neonatal metabolism of enflurane. The urinary sodium excretion did not differ from that of infants delivered without halogenated inhalation agents given to the mothers.
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Acta Anaesthesiol Scand · Jun 1980
Case ReportsEar injury caused by elevated intratympanic pressure during general anaesthesia.
Two cases of middle-ear injury, due to sharp fluctuations of intratympanic pressure as a result of general anaesthesia with nitrous oxide are presented. A study is reported indicating that the degree of these fluctuations is a function of the concentration of nitrous oxide. In order to reduce the risk of middle-ear injury due to nitrous oxide anaesthesia, it is suggested that the lowest concentration feasible should be used where there is a history of previous ear surgery.
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Acta Anaesthesiol Scand · Jun 1980
Comparative StudyCyclic AMP and metabolic substrates following hemorrhage in awake and anesthetized rats.
The levels of several metabolites in plasma were studied during a period of 4 h in awake and barbiturate anesthetized rats after a blood volume loss of approximately 3% of b.w. Blood pressure was 70 mmHg (9.3 kPa) in the awake and 35 mmHg (4.7 kPa) in the anesthetized rats. Resting levels of plasma glucose, blood lactate and pyruvate and plasma cyclic AMP were higher in the awake rats than in the anesthetized rats. ⋯ The initial changes in plasma metabolite levels appeared to be directly related to changes in plasma catecholamine levels. There were no differences in the relationship between the adrenaline level and cyclic AMP or glucose increase, suggesting that anesthesia did not alter beta-adrenoceptor sensitivity, but only catecholamine concentrations. The results also indicate that awake rats tolerate long-lasting blood volume loss better than anesthetized rats, because the sympatho-adrenal activation is more short-lasting.