Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialSpinal, epidural or propofol anaesthesia for out-patient knee arthroscopy?
We have compared three different methods of anaesthesia for out-patient knee arthroscopy in terms of perioperative conditions, postoperative pain, time taken and economy. ⋯ Propofol anaesthesia results in the shortest stay in the operation theatre but a higher degree of postoperative pain and a higher cost of drugs and disposables.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of ondansetron and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women. A randomised, double-blind, placebo-controlled trial.
Women undergoing laparoscopic surgery are susceptible to postoperative nausea and vomiting (PONV). Ondansetron and droperidol are useful antiemetics. This study was designed to ascertain primarily the relative difference in efficacy of ondansetron and droperidol and secondarily between these drugs and placebo in the prevention of PONV after laparoscopic surgery. ⋯ The efficacy of prophylactic ondansetron and droperidol in reducing postoperative nausea associated with laparoscopic surgery in female inpatients was similar, but ondansetron appeared to be slightly more efficient than droperidol in preventing vomiting. Ondansetron and droperidol were both significantly better than placebo in the prophylaxis of PONV.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of the effect of intravenous ketoprofen, ketorolac and diclofenac on platelet function in volunteers.
Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin synthesis which may result in impaired platelet function. Because NSAIDs have different abilities to inhibit cyclo-oxygenases we compared the effect of intravenous ketoprofen, ketorolac and diclofenac on platelet function in volunteers. ⋯ Ketoprofen, ketorolac and diclofenac caused a reversible platelet dysfunction. Diclofenac had the mildest effect, while platelet dysfunction was still seen 24 h after the beginning of ketorolac.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialEmergence from isoflurane/N2O or isoflurane anaesthesia.
The first goal of anaesthetic recovery is return of the patient's ability to independently maintain respiratory and circulatory functions. Nitrous oxide remains popular due to minor effects on the cardiovascular and respiratory systems. However, diffusion hypoxaemia can occur during recovery and there is a potential advantage of providing the patient with only a potent vaporised agent. ⋯ Patients anaesthetised with only isoflurane had a longer delay until resumption of spontaneous breathing and extubation in the emergence period. Minute ventilation and carbon dioxide elimination were also significantly more suppressed throughout emergence after anaesthesia with isoflurane as compared with isoflurane/N2O.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialInfluence of anaesthesia and muscle relaxation on intubating conditions and sympathoadrenal response to tracheal intubation.
The study aimed to assess the relative influence of anaesthesia and muscle relaxation on intubating conditions and the haemodynamic and catecholamine responses to tracheal intubation. ⋯ The results of the study demonstrate that the sympathoadrenal response to intubation is attenuated by adding fentanyl (2.5 X kg[-1]) to an induction regimen with thiopentone, whereas provision of complete muscle relaxation at the adductor pollicis muscle is necessary to attain smooth intubating conditions.