Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialEmergence from isoflurane/N2O or isoflurane anaesthesia.
The first goal of anaesthetic recovery is return of the patient's ability to independently maintain respiratory and circulatory functions. Nitrous oxide remains popular due to minor effects on the cardiovascular and respiratory systems. However, diffusion hypoxaemia can occur during recovery and there is a potential advantage of providing the patient with only a potent vaporised agent. ⋯ Patients anaesthetised with only isoflurane had a longer delay until resumption of spontaneous breathing and extubation in the emergence period. Minute ventilation and carbon dioxide elimination were also significantly more suppressed throughout emergence after anaesthesia with isoflurane as compared with isoflurane/N2O.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of ondansetron and droperidol in the prevention of postoperative nausea and vomiting after laparoscopic surgery in women. A randomised, double-blind, placebo-controlled trial.
Women undergoing laparoscopic surgery are susceptible to postoperative nausea and vomiting (PONV). Ondansetron and droperidol are useful antiemetics. This study was designed to ascertain primarily the relative difference in efficacy of ondansetron and droperidol and secondarily between these drugs and placebo in the prevention of PONV after laparoscopic surgery. ⋯ The efficacy of prophylactic ondansetron and droperidol in reducing postoperative nausea associated with laparoscopic surgery in female inpatients was similar, but ondansetron appeared to be slightly more efficient than droperidol in preventing vomiting. Ondansetron and droperidol were both significantly better than placebo in the prophylaxis of PONV.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialShould nitrous oxide be discontinued before desflurane after anaesthesia with desflurane/N2O?
The appearance of hypoxaemia immediately after anaesthesia with nitrous oxide may be partially explained by diffusion hypoxia. This study was undertaken to evaluate circulatory and respiratory variables during emergence after desflurane/nitrous oxide anaesthesia, and whether there are any differences depending on which gas is discontinued first. ⋯ Irrespective of which agent was discontinued first there was an increase in cardiac output decrease in oxygenation and a modest acidosis in the first 30-min recovery period. The only significant difference between the groups was in mean arterial blood pressure in the early emergence phase with a greater MAP when N2O had been used until the conclusion of anaesthesia.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialSpinal, epidural or propofol anaesthesia for out-patient knee arthroscopy?
We have compared three different methods of anaesthesia for out-patient knee arthroscopy in terms of perioperative conditions, postoperative pain, time taken and economy. ⋯ Propofol anaesthesia results in the shortest stay in the operation theatre but a higher degree of postoperative pain and a higher cost of drugs and disposables.
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Acta Anaesthesiol Scand · Nov 1997
Randomized Controlled Trial Clinical TrialThe effect of succinylcholine on atracurium-induced neuromuscular block.
The interaction between prior succinylcholine and atracurium has been found only after full recovery of succinylcholine block. We investigated whether the effect of succinylcholine on atracurium block may depend on the level of recovery from succinylcholine. ⋯ The effect of prior administration of succinylcholine on atracurium block depends on the state of recovery from succinylcholine and concerns both its potency, onset and duration characteristics.