Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 2002
Atracurium and vecuronium block nicotine-induced carotid body chemoreceptor responses.
Vecuronium depresses carotid body chemosensitivity during hypoxia. We hypothesized that this is caused by inhibition of cholinergic transmission of the carotid body. ⋯ Atracurium and vecuronium in equipotent concentrations block nicotine-induced chemoreceptor responses of the carotid body.
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Acta Anaesthesiol Scand · May 2002
Case ReportsTachycardia and convulsions induced by accidental intravascular ropivacaine injection during sciatic block.
Ropivacaine, a recently introduced local anesthetic of the amide family (1), seems to show less toxicity than bupivacaine (2-4). Nevertheless, both neurologic and cardiovascular toxicities are possible. Six cases of ropivacaine-induced convulsions have previously been reported (5-10), of which three cases also showed cardiovascular toxicity. In three cases, total plasma concentrations were measured (Table 1).
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Acta Anaesthesiol Scand · May 2002
Clinical TrialHeart rate to arterial pressure impulse response during one lung ventilation.
Although one lung ventilation (OLV) is commonly used, little is known about the modulation of the autonomic nervous system with OLV while under general anesthesia. As the frequency domain and time domain analyses are powerful analytic tools, we investigated their modulation during OLV. ⋯ Impulse response analysis demonstrated that there is a greater effect on autonomic nervous system modulation during right OLV than in left OLV, which mainly results from a parasympathetic neural linkage origin.