Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2003
Randomized Controlled Trial Clinical TrialThe effects of hydroxyethyl starch solutions on thromboelastography in preoperative male patients.
Hydroxyethyl starches (HES) have been shown to decrease clot strength and to increase coagulation times assessed by thromboelastography (TEG). HES with minimal anticoagulant side-effects is beneficial for plasma volume expansion in the perioperative setting. A comparison of the in vivo effects of high, middle and low molecular weight HES solutions on TEG variables has not been performed so far. ⋯ Infusion of HES 450/0.7/4.6 compromises TEG parameters more than the other solutions tested, whereas HES 130/0.4/9 has the smallest effect. Further outcome-related studies are needed in order to assess the clinical relevance of our findings.
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Acta Anaesthesiol Scand · Jan 2003
Randomized Controlled Trial Comparative Study Clinical TrialComparison of epidural, continuous femoral block and intraarticular analgesia after anterior cruciate ligament reconstruction.
The purpose of this study was to compare three locoregional techniques of pain management after arthroscopic anterior cruciate ligament reconstruction (ACLR). ⋯ We conclude that either epidural or continuous femoral nerve block provide adequate pain relief in patients who undergo ACLR, whereas intraarticular analgesia seems unable to cope satisfactorily with the analgesic requirements of this surgical procedure.
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Acta Anaesthesiol Scand · Jan 2003
Randomized Controlled Trial Comparative Study Clinical TrialComparison of granisetron and granisetron plus dexamethasone for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.
Laparoscopic cholecystectomies are associated with an appreciably high rate of postoperative nausea and vomiting (PONV). This study was designed to compare the effectiveness of granisetron plus dexamethasone with granisetron alone for the prevention of postoperative nausea and vomiting in patients after laparoscopic cholecystectomy. ⋯ The combination (granisetron plus dexamethasone) further increases the chance of complete response than granisetron alone. Therefore, the combination might be considered clinically relevant in a high risk setting.
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Acta Anaesthesiol Scand · Jan 2003
Clinical TrialPreoperative emotional states in patients with breast cancer and postoperative pain.
The present study examined the relationship between psychological variables, including anxiety, depression, and patient-controlled analgesia (PCA) use in patients who underwent radical mastectomy. ⋯ Patients with higher anxiety and depression levels had higher postoperative pain and analgesic requirements in this study.
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Acta Anaesthesiol Scand · Jan 2003
Case ReportsFunctional improvement after physiotherapy with a continuous infusion of local anaesthetics in patients with complex regional pain syndrome.
Three patients were referred to our pain clinic with evidence of complex regional pain syndrome in their extremities. Two presented at the atrophic stage with joint contractures. Multiple analgesics had been prescribed without long-lasting relief. ⋯ We instituted local anaesthetic infusion with the possibility of self-supplementation to facilitate physiotherapy; two via brachial plexus catheters for hand pain and one via epidural catheter for knee pain. Although their resultant pain scores were variable after cessation of local anaesthetic infusion, all the affected joints exhibited marked improvement in range of movement. We propose that this technique is a useful option for patients in all stages of complex regional pain syndrome where the emphasis is now directed toward functional improvement.