Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2004
Randomized Controlled Trial Clinical TrialLow-dose bupivacaine with sufentanil prevents hypotension after spinal anesthesia for hip repair in elderly patients.
Hip fracture is common in the geriatric population. Patients in this group are often at high risk for perioperative complications from concurrent diseases. Conventional spinal anesthesia can be associated with hypotension but has a better postoperative outcome compared to general anesthesia. We judged that a reduced dose of bupivacaine in combination with sufentanil could give reliable blocks with minimal hypotension. ⋯ A reduced dose of hyperbaric bupivacaine (7.5 mg) in combination with sufentanil (5 microg) provides reliable spinal anesthesia for the repair of hip fracture in aged patients with few events of hypotension and little need for vasopressor support of blood pressure.
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Acta Anaesthesiol Scand · Nov 2004
Randomized Controlled Trial Clinical TrialDixyrazine for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.
The study assessed the efficacy and safety of dixyrazine, an alternative neuroleptic drug to droperidol, in the prophylaxis of postoperative nausea and vomiting (PONV). ⋯ Prophylactic dixyrazine is an effective, safe, and cheap antiemetic drug for laparoscopic cholecystectomy without involving any significant adverse events.
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Acta Anaesthesiol Scand · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialWomen report more pain on injection of a precurarization dose of rocuronium: a randomized, prospective, placebo-controlled trial.
The purpose of this study was to investigate whether gender influences the perception of pain on injection of rocuronium. ⋯ Women experienced more pain on injection of rocuronium than men, moreover this is an additional evidence for gender-related differences in pain perception. When rocuronium is used as a precurarization agent, an analgesic pretreatment (e.g. opioids) should be considered, especially for female patients.
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Acta Anaesthesiol Scand · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison of the analgesic efficacy of ketobemidone and morphine for management of postoperative pain in children: a randomized, controlled study.
Ketobemidone has been used as an analgesic for postoperative pain in children, but to our knowledge the effect and occurrence of adverse effects of ketobemidone compared to morphine is not known. The aim was to determine if the analgesic potency and the occurrence of adverse effects of ketobemidone differ from morphine when administered to children, as measured by patient-controlled analgesia consumption (PCA) for postoperative pain. ⋯ The analgesic potency and adverse effects of ketobemidone are similar to morphine when used for postoperative pain management in children.
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Acta Anaesthesiol Scand · Nov 2004
Randomized Controlled Trial Clinical TrialEffects of subanaesthetic and anaesthetic doses of sevoflurane on regional cerebral blood flow in healthy volunteers. A positron emission tomographic study.
We tested the hypothesis that escalating drug concentrations of sevoflurane are associated with a significant decline of cerebral blood flow in regions subserving conscious brain activity, including specifically the thalamus. ⋯ At sevoflurane concentrations at 0.7% and 2.0% a significant decrease in relative rCBF was detected in the thalamus. Interestingly, some of the most profound changes in rCBF were observed in structures related to pain processing (anterior cingulate and insula).