Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2004
Randomized Controlled Trial Clinical TrialChanges in cerebral oxygenation during cold (28 degrees C) and warm (34 degrees C) cardiopulmonary bypass using different blood gas strategies (alpha-stat and pH-stat) in patients undergoing coronary artery bypass graft surgery.
Impaired cerebral oxygenation, which is reflected by measuring jugular bulb oxygenation, is thought to play an important role in the development of neurological injury after cardiac operations with cardiopulmonary bypass (CPB). The effects of cardiopulmonary temperature and blood gas strategy on cerebral oxygenation are not fully appreciated. ⋯ Cold CPB failed to offer any further brain protection in terms of better preservation of cerebral oxygenation than warm CPB. Therefore, warm CPB (34 degrees C) with different blood gas strategies appears to be a satisfactory alternative to cold CPB (28 degrees C).
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Acta Anaesthesiol Scand · Aug 2004
Adrenaline administration during cardiopulmonary resuscitation: poor adherence to clinical guidelines.
Adrenaline does not appear to improve the outcome after cardiac arrest in clinical trials in spite of beneficial effects in experimental studies. The objective of this study was to determine whether adrenaline was administered in accordance with advanced cardiac life support (ACLS) guidelines during adult cardiopulmonary resuscitation (CPR). ⋯ In the majority of cases adrenaline did not appear to be administered according to current ACLS guidelines.
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Acta Anaesthesiol Scand · Aug 2004
Pulmonary gas distribution during ventilation with different inspiratory flow patterns in experimental lung injury -- a computed tomography study.
There is still controversy about the optimal inspiratory flow pattern for ventilation of patients with acute lung injury. The aim of this study was to compare the effects of pressure-controlled ventilation (PCV) with a decelerating inspiratory flow with volume-controlled ventilation (VCV) with constant inspiratory flow on pulmonary gas distribution (PGD) in experimentally induced ARDS. ⋯ In this model of acute lung injury, ventilation with decelerating inspiratory flow had no beneficial effects on PGD when compared with ventilation with constant inspiratory flow, while the increase in overinflated lung volumes may raise concerns regarding potential ventilator-associated lung injury.
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Acta Anaesthesiol Scand · Aug 2004
Can chronic poststernotomy pain after cardiac valve replacement be reduced using thoracic epidural analgesia?
The aim of our study was to evaluate the use of thoracic epidural analgesia (TEA) in acute pain management after cardiac valve replacement and determine if the incidence of chronic pain related to the sternotomy was reduced by the use of TEA. This patient group was chosen to exclude pain related to the use of the internal mammary artery and angina pectoris. ⋯ We found in our small material that TEA provided excellent analgesia in the peri- and postoperative period, but we did not find a protective effect of TEA on chronic poststernotomy pain, neither weak pain nor severe pain.