Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2010
Multicenter StudyLactate concentrations in the rectal lumen in patients in early septic shock.
Previously, we observed that rectal luminal lactate was higher in non-survivors compared with survivors of severe sepsis or septic shock persisting >24 h. The present study was initiated to further investigate this tentative association between rectal luminal lactate and mortality in a larger population of patients in early septic shock. ⋯ In this prospective, observational study of unselected patients with early septic shock, there was no difference in the concentration of lactate in the rectal lumen between non-survivors and survivors.
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Acta Anaesthesiol Scand · Aug 2010
Randomized Controlled TrialNorepinephrine causes a pressure-dependent plasma volume decrease in clinical vasodilatory shock.
Recent experimental studies have shown that a norepinephrine-induced increase in blood pressure induces a loss of plasma volume, particularly under increased microvascular permeability. We studied the effects of norepinephrine-induced variations in the mean arterial pressure (MAP) on plasma volume changes and systemic haemodynamics in patients with vasodilatory shock. ⋯ Norepinephrine causes a pressure-dependent decrease in the plasma volume in patients with vasodilatory shock most likely caused by transcapillary fluid extravasation.
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Acta Anaesthesiol Scand · Aug 2010
Randomized Controlled TrialCuffed endotracheal tubes in children reduce sevoflurane and medical gas consumption and related costs.
This study aims to evaluate sevoflurane and anaesthetic gas consumption using uncuffed vs. cuffed endotracheal tubes (ETT) in paediatric surgical patients. ⋯ The use of cuffed ETT in children significantly reduced the costs of sevoflurane and medical gas consumption during anaesthesia. Increased costs for cuffed compared with uncuffed ETT were completely compensated by a reduction in sevoflurane and medical gas consumption.
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Acta Anaesthesiol Scand · Aug 2010
Induced hypothermia in comatose survivors of asphyxia: a case series of 14 consecutive cases.
Induced hypothermia is widely used for comatose survivors of cardiac arrest. Other causes of hypoxic brain injury carry a poor prognosis when treated using traditional methods. At our hospital, hypothermia has also been used for the management of all comatose survivors of asphyxiation. The aim of the present study was to report the results of the management of these patients. ⋯ The results of this study suggest that an early abnormal CT scan of the brain in patients resuscitated after asphyxiation carries an adverse prognosis. The favorable outcome of the patients in the present study suggests that a randomized clinical trial on the use of induced hypothermia in patients exposed to severe asphyxia might be warranted.
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Acta Anaesthesiol Scand · Aug 2010
Comparative StudyA clinical prospective comparison of anesthetics sensitivity and hemodynamic effect among patients with or without obstructive jaundice.
To compare isoflurane anesthesia in patients with or without hyperbilirubinemia undergoing hepatobiliary surgery. ⋯ Patients with obstructive jaundice have an increased sensitivity to isoflurane, more hypotension and bradycardia during anesthesia induction and maintenance and a prolonged recovery time compared with controls.