Acta anaesthesiologica Scandinavica
-
Acta Anaesthesiol Scand · Oct 2011
ReviewDetermining authorship in multicenter trials: a systematic review.
The practical and ethical issues in determining authorship in multicenter trials raise significant and unique challenges. This systematic review examines methods of assigning authorship in multicenter clinical trials. A literature search (October 2009) was conducted to identify articles with the terms 'authorship' and 'clinical trial,' 'multicenter' or 'multicentre.' Abstracts were reviewed for potential relevance and the complete manuscript was obtained where indicated. ⋯ The authors propose a guide for determining authorship based on the methods identified and the number of collaborators and anticipated publications. For smaller collaborative groups (e.g. <10 persons), byline inclusion of all authors based on relative contributions is recommended. For larger collaborations (e.g. ≥ 10 persons), authorship guidelines should be explicit from the outset of the trial with consideration of relevant scoring systems.
-
Acta Anaesthesiol Scand · Oct 2011
Risk factors for 1-year mortality in patients with nontraumatic intracranial hemorrhage requiring intensive care.
Mortality in patients with intracranial hemorrhage remains high. The aim of this study was to determine the 1-year survival and potential risk factors for 1-year mortality in patients with nontraumatic intracranial hemorrhage requiring intensive care. ⋯ In addition to decreased level of consciousness on admission, renal failure during the ICU stay is an independent risk factor for 1-year mortality in nontraumatic SAH as well as ICH.
-
Acta Anaesthesiol Scand · Oct 2011
Effect of patient position and PEEP on hepatic, portal and central venous pressures during liver resection.
It has been suggested that blood loss during liver resection may be reduced if central venous pressure (CVP) is kept at a low level. This can be achieved by changing patient position but it is not known how position changes affect portal (PVP) and hepatic (HVP) venous pressures. The aim of the study was to assess if changes in body position result in clinically significant changes in these pressures. ⋯ Changes of body position resulted in marked changes in CVP but not in HVPs. Head down or head up tilt to reduce venous pressures in the liver may therefore not be effective measures to reduce blood loss during liver surgery.
-
Acta Anaesthesiol Scand · Oct 2011
Movement-evoked breakthrough cancer pain despite intrathecal analgesia: a prospective series.
Intrathecal analgesia (ITA) is a valuable treatment option for intractable cancer-related pain. However, the issue of movement-evoked breakthrough pain (BTP) has not been specifically investigated in the ITA setting. The aim of the study was to evaluate the effect of ITA on spontaneous resting pain intensity (SRPI), doses of non-ITA opioids, and specifically on movement-evoked pain intensity (MEPI). ⋯ Movement-evoked BTP was a major clinical problem throughout the study month despite otherwise successful ITA. Improving the quality of life of patients with intractable cancer-related pain should include developing strategies to better deal with movement-evoked BTP.
-
Acta Anaesthesiol Scand · Oct 2011
Randomized Controlled Trial Comparative StudyGlideScope videolaryngoscope vs. Macintosh direct laryngoscope for intubation of morbidly obese patients: a randomized trial.
Morbidly obese patients are at increased risk of hypoxemia during tracheal intubation because of increased frequency of difficult and impossible intubation and a decreased apnea tolerance. In this study, intubation with the GlideScope videolaryngoscope (GS) was compared with the Macintosh direct laryngoscope (DL) in a group of morbidly obese patients. ⋯ Intubation of morbidly obese patients with GS was slightly slower than with DL. The increased intubation time was of no clinical consequence as no patients became hypoxemic. Both devices generally performed well in the studied population, but the GS provided better laryngoscopic views and decreased IDS scores.