Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Oct 2011
H-index is a sensitive indicator of academic activity in highly productive anaesthesiologists: results of a bibliometric analysis.
H-index distinguishes differences in scholarly output across faculty ranks in anaesthesiologists, but whether h-index also identifies differences in other aspects of productivity is unknown. We tested the hypothesis that h-index is an indicator of not only publication record, but also grant funding and mentoring in highly productive US academic anaesthesiologists. ⋯ In addition to publication record, h-index sensitively indicates grant funding and mentoring in highly productive US academic anaesthesiologists.
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Acta Anaesthesiol Scand · Oct 2011
Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5(+) cardiac progenitor cells.
Cardiac progenitor cells (CPCs) derived from human embryonic stem cells (hESCs) can multiply and generate cardiomyocytes, offering their tremendous potential for cardiac regenerative therapy. However, poor survival under stressful conditions is a major hurdle in the regeneration. We investigated whether isoflurane-induced preconditioning can increase hESC-derived CPC survival under oxidative stress. ⋯ Isoflurane increased hESC-derived Nkx2.5(+) CPC survival under oxidative stress, and mitoK(ATP) channels may be involved in the protective effect.