Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Aug 2015
Randomized Controlled TrialTransversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy: a randomised clinical trial.
Transversus abdominis plane (TAP) block is widely used as a part of pain management after various abdominal surgeries. We evaluated the effect of TAP block as an add-on to the routine analgesic regimen in patients undergoing robot-assisted laparoscopic hysterectomy. ⋯ In our study, the TAP block combined with paracetamol and Nonsteroidal anti-inflammatory drugs (NSAID) treatment, had no effect on morphine consumption, VAS pain scores, or frequency of nausea and vomiting after robot-assisted laparoscopic hysterectomy compared with paracetamol and NSAID alone.
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Acta Anaesthesiol Scand · Aug 2015
Multicenter Study Observational StudyVariability in targeted arterial oxygenation levels in patients with severe sepsis or septic shock.
Supplemental oxygen therapy is used for intensive care (ICU) patients with severe sepsis, but with no general guidelines and few safety data. The aim of this observational study was to describe the variability in oxygen administration as well as the association between partial pressure of arterial oxygen (PaO2 ) and mortality. ⋯ Administration of oxygen in patients with severe sepsis resulted in a wide range of PaO2 . Significantly higher mortality was observed in patients with an average PaO2 < 8 kPa and FiO2 ≥ 0.60. The results do not imply causation and the associations between average PaO2 and adverse outcomes have to be assessed further.
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Acta Anaesthesiol Scand · Aug 2015
Review Meta AnalysisPeripherally applied opioids for postoperative pain: evidence of an analgesic effect? A systematic review and meta-analysis.
Opioids applied peripherally at the site of surgery may produce postoperative analgesia with few side effects. We performed this systematic review to evaluate the analgesic effect of peripherally applied opioids for acute postoperative pain. ⋯ Evidence of a clinically relevant analgesic effect of peripherally applied opioids for acute postoperative pain is lacking. The analgesic effect of peripherally applied opioids may depend on the presence of preoperative inflammation.