Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 1975
Effect of dihydroergotamine on perpheral circulation during epidural anaesthesia in man.
The effect of intravenous administration of dihydroergotamine (DHE) on regional blood flow in the forearm and calf after pharmacological nerve blockade of the lower body induced by epidural anaesthesia has been studied in 13 subjects. After anaesthesia, DHE induced a significant increase in blood flow in the forearm with intact innervation and a significant decrease in blood flow in the nerve-blocked calf. ⋯ In the intact forearm, local vascular resistance decreased. The results indicate that DHE exerts a complex effect on resistance vessels in addition to its well-known effect on the capacitance vessels.
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Acta Anaesthesiol Scand · Jan 1975
Epidural anaesthesia as an alternative to caesarean section in the treatment of prolonged, exhaustive labour.
Epidural anaesthesia was given to nine parturients who were considered candidates for delivery by caesarena section due to prolonged exhaustive labour. Upon pain relief and oxytocin infucion guided by cardiotocography, vaginal delivery took place. Delivery was spontaneous in seven cases, two were instrumentally delivered. It is concluded that an efficient epidural block tends to restore uterine contractility by reducing the inhibitory influences exerted by adrenergic mechanisms and unfavourable changes in the acid-base balance.
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Acta Anaesthesiol Scand · Jan 1975
The influence of arterial carbon dioxide tension on the cerebrovascular response to arterial hypoxia and to haemodilution.
Cerebral blood flow (CBF) measurements and blood gas analyses were performed on anaesthetized and artifically ventilated dogs during arterial hypoxia or haemodilution in different ranges of arterial carbon dioxide tension. Arterial hypoxia as well as haemodilution produced a flow increase in all ranges of ventilation. ⋯ On the assumption that the cerebrovenous oxygen tension reflects the oxygen tension of the brain tissue, it is suggested that the arterial carbon dioxide tension influences the ability of the brain tissue to maintain the aerobic metabolism during reduced tissue oxygen tension. This means that tissue hypoxia, in the sense of utilisation of anaerobic metabolism, occurs at a tissue oxygen tension which is lower the lower the arterial carbon dioxide tension is.
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Acta Anaesthesiol Scand · Jan 1975
Electroencephalographic activity in children under enflurane anesthesia.
EEG, end-tidal CO2, neck muscle EMG, eye movements, and ECG were recorded in 17 children undergoing enflurane anesthesia combined with N2O and O2. All subjects were classified in the lowest risk group and had normal pre-anesthetic EEG recordings. Eleven subjects were breathing spontaneously and six were under controlled ventilation. ⋯ At 3% enflurane, three out of eight subjects showed electrographic seizure activity of poly-spike-suppression type. One of these children also had motor manifestations during this type of seizure activity at a PaCO2 of 31 mmHg. The results indicate that electrographic seizure activity is common among children with moderate hypocapnia at enflurane concentrations of 3% or more.