Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 1997
Paediatric cardiac arrest and resuscitation provided by physician-staffed emergency care units.
Most paediatric cardiac arrest studies have been conducted in the USA, where paramedics provide prehospital emergency care. We wanted to study the outcome of paediatric cardiac arrest patients in an emergency medical system which is based on physician staffed emergency care units. ⋯ Although prehospital care was provided by physicians, the overall rate of survival was found to be equally poor as reported from systems with paramedics. The only major difference between physician- and paramedic-staffed emergency care units is the ability of physicians to refrain from resuscitation already on the scene when prognosis is poor.
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Acta Anaesthesiol Scand · Feb 1997
Randomized Controlled Trial Clinical TrialThe influence of the duration of isoflurane anaesthesia on neuromuscular effects of mivacurium.
The pharmacodynamic profile of muscle relaxants is usually changed by volatile anaesthetics. These changes seem to be time-dependent, even though few data are available to substantiate this. ⋯ Our results indicate that the duration of a constant concentration of isoflurane anaesthesia influences significantly the pharmacodynamics of mivacurium. The duration of a volatile anaesthesia is critical when potentiation of NMB is evaluated or compared in neuromuscular studies.
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Acta Anaesthesiol Scand · Feb 1997
Fibreoptic laryngotracheoscopy via the laryngeal mask airway in children.
Fibreoptic laryngotracheoscopy via the laryngeal mask airway-previously reported in adults but not in children-gives a better endoscopic view of the upper airway than does endoscopy via an endotracheal tube. ⋯ In children anaesthetized with halothane, flexible fibreoptic laryngotracheoscopy via a laryngeal mask is a useful method-offering technical advantages not achieved otherwise-provided that generally approved restrictions to the use of a laryngeal mask airway are taken into account.
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Acta Anaesthesiol Scand · Feb 1997
Randomized Controlled Trial Clinical TrialMetoclopramide reduces the induction dose of propofol.
Metoclopramide has been shown to reduce the dose of thiopentone required for induction of anaesthesia. When propofol is used, there have been conflicting results with one small study showing a reduction in the anaesthetic dose and one study failing to demonstrate any effect. ⋯ The mechanism of reduction of propofol dose by metoclopramide is unknown; it may involve GABA or result from a more complex interaction involving dopamine blockade by metoclopramide.
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Acta Anaesthesiol Scand · Feb 1997
Intravenous induction of general anaesthesia with eltanolone in children 6-15 years of age.
Eltanolone is a short-acting intravenous anaesthetic, formulated as an oil-water emulsion. The aim of the present study was to estimate the anaesthetic dose (ED50) for induction in children 6-10 and 11-15 years of age and to collect safety data. ⋯ The ED50 of eltanolone for induction of anaesthesia in unpremedicated children 6-10 years of age was 0.68 mg/kg and in children 11-15 years of age 0.53 mg/kg. The findings suggest that an induction dose for children 6-15 years of age of about 1 mg/kg would be adequate in most cases. No serious adverse events were recorded. However, the drug has subsequently been withdrawn from further investigation due to an unacceptable incidence of rash and urticaria.