Annals of oncology : official journal of the European Society for Medical Oncology

The most recent articles from: Ann. Oncol. January 2012

Ann. Oncol. · Jan 2012

Randomized Controlled Trial

Efficacy of venlafaxine for the prevention and relief of oxaliplatin-induced acute neurotoxicity: results of EFFOX, a randomized, double-blind, placebo-controlled phase III trial.

Oxaliplatin neurosensory toxicity is dose limiting and may present as acute symptoms and/or cumulative peripheral neuropathy. ⋯ Venlafaxine has clinical activity against oxaliplatin-induced acute neurosensory toxicity.

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