Acta dermato-venereologica
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Acta Derm. Venereol. · Jan 1984
Skin manifestations of tularemia: a study of 88 cases in northern Finland during 16 years (1967-1983).
88 tularemia patients with secondary skin manifestations seen in northern Finland during 1967-1983 are described in this paper. Tularemia was ulceroglandular in 57% and pulmonary in 27% of the patients. 68% of the patients were women. The most common secondary skin manifestation was papular or vesicopapular eruption which was seen in 42% of the patients. ⋯ Erythema nodosum was seen more often in patients with pulmonary tularemia than in other types of the disease (p less than 0.01). The clinical pictures of erythema nodosum and erythema multiforme caused by tularemia greatly resembled those caused by Yersinia. Tularemia should be remembered as one possible triggering factor of erythema nodosum and erythema multiforme.
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Acta Derm. Venereol. · Jan 1984
Loss of bullous pemphigoid antigen in peritumoral lacunas of basal cell carcinomas.
Peritumoral lacunas of basal cell carcinoma (BCC) were for a long time misinterpreted as fixation artifacts. However, recent studies showed that they might be considered as a dynamic process related to degenerescence for the palisade cells. We studied three antigens of the epidermal basement membrane zone--type IV collagen, laminin, and bullous pemphigoid antigen--by indirect immunofluorescence in six cases of basal cell carcinoma. ⋯ Bullous pemphigoid antigen showed either a linear continuous or discontinuous staining pattern along the basement membrane zone of the carcinomatous buds. At the site of a peritumoral lacuna bullous pemphigoid antigen abruptly disappeared. The loss of bullous pemphigoid antigen might be related to the lacuna formation.