The Journal of craniofacial surgery
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Acute or chronic laryngitis, laryngeal trauma, vocal cord paralysis, cysts of the vocal cord, and benign or malignant tumors of the vocal folds are frequent causes of hoarseness. It is important to identify the cause of hoarseness to rule out potential malignancies. ⋯ Behcet disease is characterized by mucosal aphthous lesions, which are found primarily in oral and genital regions. To the best of our knowledge, this is the first instance of a patient with bilateral aphthous ulcer in the vocal cords.
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Hemi-craniectomy is a common surgical procedure which allows the brain to swell and herniate and is often utilized to treat traumatic brain injury. When left untreated the scalp skin typically sinks on the side of the craniectomy creating a phenotype termed "sinking skin flap syndrome." In addition, these same patients often develop long-term neurocognitive deficits termed "syndrome of the trephined" as a result of their craniectomy which reverse when the cranial skull is replaced. The authors hypothesize that a mouse animal model can be developed demonstrating long-term neurologic deficits attributed to hemi-craniectomy skull defects similar to humans with syndrome of the trephined. ⋯ Motor deficits that are attributed to hemi-craniectomy bone defects alone are demonstrated in a mouse animal model. These motor deficits resemble some symptoms associated with human syndrome of the trephined.